SOP保守勃起功能障碍(医学和机械)治疗

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所属分类:医学快讯
摘要

勃起功能障碍(ED)是最常见的治疗男性性功能障碍全球。 ED是发挥产生负面影响一种慢性疾病,…

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摘要

介绍

勃起功能障碍(ED)是最经常治疗男性性功能障碍全世界。 ED是一种慢性疾病,其施加对男性的自尊和几乎所有的生活领域,包括人际,家庭和商业关系产生负面影响。

目的

本研究的目的是提供对ED当前使用和可用保守治疗方案,特别着重于最新概览其疗效,耐受性,安全性,优点和限制,包括单药治疗失败的联合治疗的作用。

的方法

[ 123]所使用的方法是使用以下关键词PubMed和MEDLINE搜索:ED,5型磷酸二酯酶(PDE5)抑制剂,口服药物吨herapy,海绵体内注射疗法,经尿道治疗,局部疗法,并真空勃起疗法/收缩装置。另外,通过本文的作者专家意见也包括在内。

结果

1级证据存在于久坐的生活方式与伴随疾病/风险因素的体重减轻和最佳的治疗的改变(例如,糖尿病,高血压,和血脂异常)可以提高ED或添加到ED-特定疗法,例如,PDE5抑制剂的功效。电平1的证据也存在与总睾酮该治疗性腺功能减退症的

PORST H,伯内特A,布洛克G,加尼姆H,朱楼格利纳S,赫尔斯特伦W,马丁-Morales的A,Salonia A,Sharlip I和ISSM标准委员会对性医学。 SOP保守(医疗和米器的机械)治疗勃起功能障碍。 Ĵ性别医学2013; 10:130-171 < 300 ng/dL (10.4 nmol/L) can either improve ED or add to the efficacy of PDE5 inhibitors. There is level 1 evidence regarding the efficacy and safety of the following monotherapies in a spectrum-wide range of ED populations: PDE5 inhibitors, intracavernosal injection therapy with prostaglandin E1 (PGE1, synonymous alprostadil) or vasoactive intestinal peptide (VIP)/phentolamine, and transurethral PGE1 therapy. There is level 2 evidence regarding the efficacy and safety of the following ED treatments: vacuum-erection therapy in a wide range of ED populations, oral L-arginine (3–5 g), topical PGE1 in special ED populations, intracavernosal injection therapy with papaverine/phentolamine (bimix), or papaverine/phentolamine/PGE1 (trimix) combination mixtures. There is level 3 evidence regarding the efficacy and safety of oral yohimbine in nonorganic ED. There is level 3 evidence that combination therapies of PDE5 inhibitors + either transurethral or intracavernosal injection therapy generate better efficacy rates than either monotherapy alone. There is level 4 evidence showing enhanced efficacy with the combination of vacuum-erection therapy + either PDE5 inhibitor or transurethral PGE1 or intracavernosal injection therapy. There is level 5 evidence (expert opinion) that combination therapy of PDE5 inhibitors + L-arginine or daily dosing of 他达那非 + short-acting PDE5 inhibitors pro re nata may rescue PDE5 inhibitor monotherapy failures. There is level 5 evidence (expert opinion) that adding either PDE5 inhibitors or transurethral PGE1 may improve outcome of penile prosthetic surgery regarding soft (cold) glans syndrome. There is level 5 evidence (expert opinion) that the combination of PDE5 inhibitors and 达伯西汀 is effective and safe in patients suffering from both ED and premature ejaculation.

关键词

勃起DysfunctionOral药物TreatmentPhosphodiesterase InhibitorsIntracavernous自注射TherapyTransurethral前列地尔TherapyCombination TherapiesVacuum设备TherapyView全文

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